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Altered expression of ZnT10 in Alzheimers disease brain

Especially, AMPK is a potent inhibitor of the mTOR-mediated signaling, e.g., it can inhibit the MDSC-induced immunosuppressive responses, probably inhibiting the mTOR-STAT3 pathway [64]

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Given the susceptibility of the brain to radiation-induced oxidative stress, understanding the role of GPX4 in ferroptosis becomes paramount for developing potential therapeutic interventions